Level 12 Guided Question: How does Nucleic acids communicate?
Level 12 Investigation: DNA Structure
In the 1950's scientists knew of DNA, a large polymer made up of monomer units called nucleotides. In 1953 James Watson and Francis Crick analyzed the sturcture of DNA by using DNA preparations and extensive x-ray data. They proposed that two coiled chanis of DNA intertwne to form a double helix and that these two strand are complementary. These strand are quite long and are twisted, coiled and tightly packed in cells or in the chromosomes in cells that have nuclei. DNA (Deoxyribonucleic acid) is the basic hereditary material in all cells and contains all the information necessary to make proteins. For this lab you and your partner will be receiving a bag a of plastic DNA building blocks (see below) watch the VDO that is below so that you know how to construct the double helix.
1. Build 16 nucleotides: 4 each of Cytosine (C) and Guanine (G) and 4 each of Adenine (A) and Thymine (T).
2. Use these nucleotide units to construct a 8 rung ladder of DNA. Match nucleotides of adenine (orange) with thymine (green) and cyostine (blue) and guanine (yellow) using white rods (hydrogen bonds). You may choose the sequence of bases, but have at least one of each color on both sides of your ladder. Have Mr. Delsol check your model before continuing. See illustrations below:
1. Build 16 nucleotides: 4 each of Cytosine (C) and Guanine (G) and 4 each of Adenine (A) and Thymine (T).
2. Use these nucleotide units to construct a 8 rung ladder of DNA. Match nucleotides of adenine (orange) with thymine (green) and cyostine (blue) and guanine (yellow) using white rods (hydrogen bonds). You may choose the sequence of bases, but have at least one of each color on both sides of your ladder. Have Mr. Delsol check your model before continuing. See illustrations below:
3. Now bond the phosphate of each nucleotide to the sugar unit of the neighboring nucleotide.
4. Once you have completed you 8 rung DNA model. Gently twist to show the 3-D nature of the double helix. 5. Complete the lab with your partner by labeling the DNA components (spelling will count) and taking a picture of it, then email it to Mr. D's. In additon, please complete the Lab Analysis ("Molecular Model of DNA") below. |
Nucleotide= phosphate + base + sugar
click on image to enlarge |
With your lab partner follow the instructions (two page instructions) below to complete your own model
Instructions Page 1
Instruction Page 2
Level 12 Elaborate:complete the Analysis for the DNA Structure in the form below
Level 12 Videos:Watch at least one of the VDos below so that you can understand each process.
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Level 12 Elaborate:Watch at least one of the VDos below so that you can understand each process.
Just watch one of the videos and use it to complete a poster of the process of Mitosis you may either make your poster into a VDO (60-90 seconds) or use the poster with the explanations under each process. Take a picture of your poster with your explanations and upload it to your Google Classroom assignment page. Do the same for your VDO!
Level 12 Review:Watch at least one of the VDos below so that you can understand each process.
Click on the buttons to review for the unit test. Make sure you know what happens in each of the processes and know all the vocabulary as well.
Level 12 Summary:Unit Test
Virtual Lab??In a perfect world, every student gets a microscope, and the teacher can project the slides so that every student knows what they are viewing. I put this activity together because this is not a perfect world.
This test is a little different that you have experienced it is a virtual lab however if you would rather use a microscope and slide you are more that welcome. Please read and follow the instruction your grade depends on how well you take instruction on your own. To upload your products go to your Google Classroom page and post there.
Click the button to begin.
This test is a little different that you have experienced it is a virtual lab however if you would rather use a microscope and slide you are more that welcome. Please read and follow the instruction your grade depends on how well you take instruction on your own. To upload your products go to your Google Classroom page and post there.
Click the button to begin.